A Rapid Binder Discovery Workflow for Engineering Mini-Protein Degraders

J Jingzhou Yang (Department of Chemistry) M Matthew J. Styles (Department of Chemistry) K Kanokpol Aphicho (Department of Chemistry) H Hajime Asada (University of Chicago Medicine Comprehensive Cancer Center) S Shodai Komatsu (Department of Chemistry) E Eddy Pineda (Department of Chemistry) S Seyyedmohsen Hosseinibarkooie (University of Chicago Proteomics Platform) B Benjamin Stein (University of Chicago Proteomics Platform) J Junko Matsuzaki (University of Chicago Medicine Comprehensive Cancer Center) K Kunle Odunsi (University of Chicago Medicine Comprehensive Cancer Center) T Takemasa Tsuji (University of Chicago Medicine Comprehensive Cancer Center) B Bryan C. Dickinson (Department of Chemistry)

Article Details

Volume / Issue Vol. 148, Issue 21
Published June 03, 2026
Pages 21444-21456
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (12)

J

Jingzhou Yang

Department of Chemistry

M

Matthew J. Styles

Department of Chemistry

K

Kanokpol Aphicho

Department of Chemistry

H

Hajime Asada

University of Chicago Medicine Comprehensive Cancer Center

S

Shodai Komatsu

Department of Chemistry

E

Eddy Pineda

Department of Chemistry

S

Seyyedmohsen Hosseinibarkooie

University of Chicago Proteomics Platform

B

Benjamin Stein

University of Chicago Proteomics Platform

J

Junko Matsuzaki

University of Chicago Medicine Comprehensive Cancer Center

K

Kunle Odunsi

University of Chicago Medicine Comprehensive Cancer Center

T

Takemasa Tsuji

University of Chicago Medicine Comprehensive Cancer Center

B

Bryan C. Dickinson

Department of Chemistry