A novel, covalent broad-spectrum inhibitor targeting human coronavirus Mpro

J Jing Sun D Deheng Sun Q Qi Yang D Dong Wang J Jingjing Peng H Hu Guo X Xiaoyu Ding Z Zhao Chen (Key Laboratory for Renewable Energy, Beijing Key Laboratory for New Energy Materials and Devices, Beijing National Laboratory for Condensed Matter Physics, Institute of Physics) B Bin Yuan Y Yan A. Ivanenkov J Jinwei Yuan B Bogdan A. Zagribelnyy Y Yiyun He J Jingyi Su (School of Materials Science and Engineering) L Ling Wang J Jielin Tang Z Zhun Li R Rong Li T Taotao Li X Xiaoyu Hu X Xing Liang (Department of Biology, Stanford University) A Airu Zhu P Peilan Wei Y Yaya Fan S Sang Liu J Jie Zheng (Key Laboratory of Radiation Physics and Technology, Ministry of Education, Institute of Nuclear Science and Technology) X Xin Guan A Alex Aliper M Minglei Yang D Dmitry S. Bezrukov (Department of Chemistry, Lomonosov Moscow State University 3 , Moscow 119991,) Z Zhanhong Xie V Victor A. Terentiev G Guilin Peng D Daniil A. Polykovskiy A Alexander S. Malyshev M Maxim N. Malkov Q Qingsong Zhu A Alán Aspuru-Guzik (Chemical Physics Theory Group, Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada) X Xiao Ding X Xin Cai M Man Zhang (College of Chemistry) J Jingxian Zhao N Nanshan Zhong (State Key Laboratory of Respiratory Disease National Clinical Research Center for Respiratory Disease National Center for Respiratory Medicine Guangzhou Institute of Respiratory Health Guangzhou China) F Feng Ren X Xinwen Chen A Alex Zhavoronkov J Jincun Zhao (Guangzhou National Laboratory)