A Molecular Glue Approach to Control the Half-Life of CRISPR-Based Technologies

V Vedagopuram Sreekanth (Chemical Biology and Therapeutics Science) M Max Jan (Broad Institute of Harvard and MIT) K Kevin T. Zhao (Merkin Institute of Transformative Technologies in Healthcare) D Donghyun Lim (Chemical Biology and Therapeutics Science Program) S Surached Siriwongsup (Department of Cancer Biology) J Jessie R. Davis (Merkin Institute of Transformative Technologies in Healthcare) M Marie McConkey (Department of Medical Oncology) V Veronica Kovalcik (Department of Medical Oncology) S Sam Barkal (Division of Genetics, Department of Medicine) B Benjamin K. Law (Chemical Biology and Therapeutics Science Program) J James Fife (Division of Genetics, Department of Medicine) R Ruilin Tian (Department of Biochemistry and Biophysics, Institute for Neurodegenerative Diseases) M Michael E. Vinyard (Department of Chemistry and Chemical Biology) B Basheer Becerra (Molecular Pathology Unit) M Martin Kampmann R Richard I. Sherwood (Division of Genetics, Department of Medicine) L Luca Pinello D David R. Liu B Benjamin L. Ebert (Department of Medical Oncology) A Amit Choudhary (Chemical Biology and Therapeutics Science)

Article Details

Volume / Issue Vol. 147, Issue 27
Published July 09, 2025
Pages 23844-23856
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (20)

V

Vedagopuram Sreekanth

Chemical Biology and Therapeutics Science

M

Max Jan

Broad Institute of Harvard and MIT

K

Kevin T. Zhao

Merkin Institute of Transformative Technologies in Healthcare

D

Donghyun Lim

Chemical Biology and Therapeutics Science Program

S

Surached Siriwongsup

Department of Cancer Biology

J

Jessie R. Davis

Merkin Institute of Transformative Technologies in Healthcare

M

Marie McConkey

Department of Medical Oncology

V

Veronica Kovalcik

Department of Medical Oncology

S

Sam Barkal

Division of Genetics, Department of Medicine

B

Benjamin K. Law

Chemical Biology and Therapeutics Science Program

J

James Fife

Division of Genetics, Department of Medicine

R

Ruilin Tian

Department of Biochemistry and Biophysics, Institute for Neurodegenerative Diseases

M

Michael E. Vinyard

Department of Chemistry and Chemical Biology

B

Basheer Becerra

Molecular Pathology Unit

M

Martin Kampmann

R

Richard I. Sherwood

Division of Genetics, Department of Medicine

L

Luca Pinello

D

David R. Liu

B

Benjamin L. Ebert

Department of Medical Oncology

A

Amit Choudhary

Chemical Biology and Therapeutics Science