A meta-analysis of the effects of mindfulness meditation training on self-reported interoception

I Isaac N. Treves Y Ya-Yun Chen C Caitlyn L. Wilson C Charles Verdonk J Joanne Qina`au J James E. Pustejovsky S Simon B. Goldberg W Wolf Mehling Z Zev Schuman-Olivier S Sahib S. Khalsa

Abstract

Abstract Mindfulness meditation training may cultivate interoceptive awareness and provide therapeutic benefit when implemented within mental and physical health interventions. This pre-registered meta-analysis evaluated the impact of mindfulness interventions on self-reported interoception measures and associated relationships with psychological outcomes. Twenty-nine randomized controlled trials with 2,191 participants (77.8% female, mean age 32.8 years) were meta-analyzed using correlated and hierarchical effects models. Interventions included mindfulness-based programs ( k  = 15), body-based approaches (incorporating elements like massage, k  = 8), and other variations ( k  = 6). Five SIMs were tested; the Multidimensional Assessment of Interoceptive Awareness was the most common (22 studies). Results showed a small-to-medium positive effect on interoception measures across all studies ( g  = 0.31, p  < 0.001, 95% CI [0.21, 0.42]) with low-to-moderate heterogeneity ( τ  = 0.16). Mindfulness-based programs demonstrated the largest effects ( g  = 0.41). No evidence of publication bias was found. No other moderators, such as practice dosage or clinical sample, were significant. Improvements in self-reported interoception were similar in size to improvements in self-reported mindfulness and were related to improvements in psychological distress. These meta-analytic findings provide evidence that mindfulness-based interventions lead to adaptive changes in the subjective experience of interoception, perhaps contributing to improved mental wellbeing.

Article Details

Volume / Issue Vol. 15, Issue 1
Published November 06, 2025
ISSN 2045-2322
Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (10)

I

Isaac N. Treves

Y

Ya-Yun Chen

C

Caitlyn L. Wilson

C

Charles Verdonk

J

Joanne Qina`au

J

James E. Pustejovsky

S

Simon B. Goldberg

W

Wolf Mehling

Z

Zev Schuman-Olivier

S

Sahib S. Khalsa