A highly potent nanobody-based bispecific therapeutic provides broad-spectrum protection against ebolavirus

M Meihua Wang X Xinghai Zhang (State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences) W Wujian Li Y Yanfeng Yao (State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences) E Entao Li (Division of Life Sciences and Medicine, University of Science and Technology of China) B Baoyue Zhang J Jinge Zhou S Shunli Liu Y Yongxiang Gao Z Zhongliang Zhu L Lixia Zhu M Mengyao Liu (State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College) J Jing Hu C Cheng Peng (College of Chemistry and Molecular Engineering) F Fangxu Li (State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences) M Miaoyu Chen (State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences) H Hang Liu (Division of Life Science, The Hong Kong University of Science and Technology, Clear Water Bay) C Chengbing Yao Y Yuhua Shang F Feihu Yan P Peng Gong T Tengchuan Jin S Sandra Chiu (Department of Infectious Disease, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China)

Article Details

Volume / Issue Vol. 17, Issue 1
Published March 17, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (23)

M

Meihua Wang

X

Xinghai Zhang

State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences

W

Wujian Li

Y

Yanfeng Yao

State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences

E

Entao Li

Division of Life Sciences and Medicine, University of Science and Technology of China

B

Baoyue Zhang

J

Jinge Zhou

S

Shunli Liu

Y

Yongxiang Gao

Z

Zhongliang Zhu

L

Lixia Zhu

M

Mengyao Liu

State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

J

Jing Hu

C

Cheng Peng

College of Chemistry and Molecular Engineering

F

Fangxu Li

State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences

M

Miaoyu Chen

State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences

H

Hang Liu

Division of Life Science, The Hong Kong University of Science and Technology, Clear Water Bay

C

Chengbing Yao

Y

Yuhua Shang

F

Feihu Yan

P

Peng Gong

T

Tengchuan Jin

S

Sandra Chiu

Department of Infectious Disease, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China