A genome-wide CRISPR screen identifies the TNRC18 gene locus as a regulator of inflammatory signaling

Fedik Rahimov; Sujana Ghosh; Sakina Petiwala; Mary Schmidt; Eugene Nyamugenda; Manman Shi; Jason Tam; Daniel Verduzco; Sanjana Singh; Victor Avram; Apexa Modi; Celso A. Espinoza; Charles Lu; Jing Wang; Ashleigh Keller; Michael Macoritto; Naim Al Mahi; Tifani Anton; Namjin Chung; Michael J. Flister; Kanstantsin V. Katlinski; Amlan Biswas; Anneke I. den Hollander; Jeffrey F. Waring; Joshua D. Stender

doi:10.1038/s41467-025-65277-y

A genome-wide CRISPR screen identifies the TNRC18 gene locus as a regulator of inflammatory signaling

F Fedik Rahimov (Genomics Research Center, AbbVie, North Chicago, IL) S Sujana Ghosh S Sakina Petiwala M Mary Schmidt E Eugene Nyamugenda M Manman Shi J Jason Tam D Daniel Verduzco S Sanjana Singh V Victor Avram A Apexa Modi C Celso A. Espinoza C Charles Lu J Jing Wang (Hunan Cancer Hospital Changsha China) A Ashleigh Keller M Michael Macoritto N Naim Al Mahi T Tifani Anton N Namjin Chung M Michael J. Flister K Kanstantsin V. Katlinski A Amlan Biswas A Anneke I. den Hollander J Jeffrey F. Waring (Genomics Research Center, AbbVie, North Chicago, IL) J Joshua D. Stender

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Article Details

Journal Nature Communications

Volume / Issue Vol. 16, Issue 1

Published November 24, 2025

DOI 10.1038/s41467-025-65277-y

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (25)

F

Fedik Rahimov

Genomics Research Center, AbbVie, North Chicago, IL

S

Sujana Ghosh

S

Sakina Petiwala

M

Mary Schmidt

E

Eugene Nyamugenda

M

Manman Shi

J

Jason Tam

D

Daniel Verduzco

S

Sanjana Singh

V

Victor Avram

A

Apexa Modi

C

Celso A. Espinoza

C

Charles Lu

J

Jing Wang

Hunan Cancer Hospital Changsha China

A

Ashleigh Keller

M

Michael Macoritto

N

Naim Al Mahi

T

Tifani Anton

N

Namjin Chung

M

Michael J. Flister

K

Kanstantsin V. Katlinski

A

Amlan Biswas

A

Anneke I. den Hollander

J

Jeffrey F. Waring

Genomics Research Center, AbbVie, North Chicago, IL

J

Joshua D. Stender

A genome-wide CRISPR screen identifies the TNRC18 gene locus as a regulator of inflammatory signaling

Article Details

Journal Info

Authors (25)

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