A Cyclometalated Gold(III) Complex Targets Mitochondrial VDAC1 to Drive Immunometabolic Reprogramming in Cancer

S Sean T. Gilpatrick (Department of Chemistry) J Jong Hyun Kim (Department of Chemistry) S Sarayu Bhogoju (Department of Medicine, Division of Digestive Diseases and Nutrition) N Neeraj Kapur (Department of Medicine, Division of Digestive Diseases and Nutrition) U Udara Munugoda (Department of Chemistry) J Jovita Daraezinwa (Department of Chemistry) S Sean Parkin (Department of Chemistry) T Terrence A. Barrett (Department of Medicine, Division of Digestive Diseases and Nutrition) C Christine F. Brainson (Department of Toxicology and Cancer Biology) D Daniel R. Plaugher (Department of Toxicology and Cancer Biology) S Samuel G. Awuah (Department of Chemistry)

Article Details

Volume / Issue Vol. 148, Issue 24
Published June 24, 2026
Pages 24669-24684
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (11)

S

Sean T. Gilpatrick

Department of Chemistry

J

Jong Hyun Kim

Department of Chemistry

S

Sarayu Bhogoju

Department of Medicine, Division of Digestive Diseases and Nutrition

N

Neeraj Kapur

Department of Medicine, Division of Digestive Diseases and Nutrition

U

Udara Munugoda

Department of Chemistry

J

Jovita Daraezinwa

Department of Chemistry

S

Sean Parkin

Department of Chemistry

T

Terrence A. Barrett

Department of Medicine, Division of Digestive Diseases and Nutrition

C

Christine F. Brainson

Department of Toxicology and Cancer Biology

D

Daniel R. Plaugher

Department of Toxicology and Cancer Biology

S

Samuel G. Awuah

Department of Chemistry