A Common Ancestry-Specific Sodium Channel Variant Increases Susceptibility to Drug-Induced QTc Prolongation: Evidence From a Large Biobank

Russell Stewart; Brandon D. Lowery; Eric Farber-Eger; Yuko Wada; Dan M. Roden; Quinn S. Wells; Giovanni Davogustto

doi:10.1161/circulationaha.125.074358

A Common Ancestry-Specific Sodium Channel Variant Increases Susceptibility to Drug-Induced QTc Prolongation: Evidence From a Large Biobank

R Russell Stewart (School of Medicine (R.S.), Vanderbilt University Medical Center, Nashville, TN.) B Brandon D. Lowery (Department of Medicine, Division of Cardiovascular Medicine (B.D.L., E.F.-E., Y.W., Q.S.W., G.D.), Vanderbilt University Medical Center, Nashville, TN.) E Eric Farber-Eger Y Yuko Wada D Dan M. Roden Q Quinn S. Wells G Giovanni Davogustto (Department of Medicine, Division of Cardiovascular Medicine (B.D.L., E.F.-E., Y.W., Q.S.W., G.D.), Vanderbilt University Medical Center, Nashville, TN.)

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Article Details

Journal Circulation

Volume / Issue Vol. 152, Issue 25

Published December 23, 2025

Pages 1806-1808

DOI 10.1161/circulationaha.125.074358

ISSN 0009-7322

Publisher Lippincott Williams & Wilkins

Journal Info

Circulation

Lippincott Williams & Wilkins

ISSN: 0009-7322 Health Sciences

Authors (7)

R

Russell Stewart

School of Medicine (R.S.), Vanderbilt University Medical Center, Nashville, TN.

B

Brandon D. Lowery

Department of Medicine, Division of Cardiovascular Medicine (B.D.L., E.F.-E., Y.W., Q.S.W., G.D.), Vanderbilt University Medical Center, Nashville, TN.

E

Eric Farber-Eger

Y

Yuko Wada

D

Dan M. Roden

Q

Quinn S. Wells

G

Giovanni Davogustto

Department of Medicine, Division of Cardiovascular Medicine (B.D.L., E.F.-E., Y.W., Q.S.W., G.D.), Vanderbilt University Medical Center, Nashville, TN.

A Common Ancestry-Specific Sodium Channel Variant Increases Susceptibility to Drug-Induced QTc Prolongation: Evidence From a Large Biobank

Article Details

Journal Info

Authors (7)

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