A Cascade-Responsive AND-Logic-Activatable Nanoprobe for Intraoperative Fluorescence Imaging of Colorectal Cancer

L Leyi Fang (State Key Laboratory of Analytical Chemistry for Life Science, Department of General Surgery & Pathology, Nanjing Drum Tower Hospital, School of Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC)) Y Yusuke Ishigaki (Department of Chemistry, Faculty of Science, Hokkaido University, N10 W8, North-ward, Sapporo 060-0810, Japan) W Weijing Huang (State Key Laboratory of Analytical Chemistry for Life Science, Department of General Surgery & Pathology, Nanjing Drum Tower Hospital, School of Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC)) K Kyosuke Sakai (Department of Chemistry, Faculty of Science, Hokkaido University, N10 W8, North-ward, Sapporo 060-0810, Japan) Z Zhonghan Xu (State Key Laboratory of Analytical Chemistry for Life Science, Department of General Surgery & Pathology, Nanjing Drum Tower Hospital, School of Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC)) T Takashi Harimoto (Institute for Molecular Science) D Dongyuan Sun (Department of General Surgery) Y Yunlong Li Y Yiqing Wang (Department of Biomedical Engineering, College of Engineering and Applied Sciences) C Chunmei Lu (State Key Laboratory of Analytical Chemistry for Life Science, Department of General Surgery & Pathology, Nanjing Drum Tower Hospital, School of Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC)) Q Qi Sun Y Yan Zhang L Luyan Wu (State Key Laboratory of Analytical Chemistry for Life Science, Department of General Surgery & Pathology, Nanjing Drum Tower Hospital, School of Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC)) M Min Feng T Takanori Suzuki (Department of Chemistry, Faculty of Science, Hokkaido University, N10 W8, North-ward, Sapporo 060-0810, Japan) D Deju Ye (State Key Laboratory of Analytical Chemistry for Life Science, Department of General Surgery & Pathology, Nanjing Drum Tower Hospital, School of Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC))

Article Details

Volume / Issue Vol. 148, Issue 16
Published April 29, 2026
Pages 17443-17458
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (16)

L

Leyi Fang

State Key Laboratory of Analytical Chemistry for Life Science, Department of General Surgery & Pathology, Nanjing Drum Tower Hospital, School of Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC)

Y

Yusuke Ishigaki

Department of Chemistry, Faculty of Science, Hokkaido University, N10 W8, North-ward, Sapporo 060-0810, Japan

W

Weijing Huang

State Key Laboratory of Analytical Chemistry for Life Science, Department of General Surgery & Pathology, Nanjing Drum Tower Hospital, School of Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC)

K

Kyosuke Sakai

Department of Chemistry, Faculty of Science, Hokkaido University, N10 W8, North-ward, Sapporo 060-0810, Japan

Z

Zhonghan Xu

State Key Laboratory of Analytical Chemistry for Life Science, Department of General Surgery & Pathology, Nanjing Drum Tower Hospital, School of Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC)

T

Takashi Harimoto

Institute for Molecular Science

D

Dongyuan Sun

Department of General Surgery

Y

Yunlong Li

Y

Yiqing Wang

Department of Biomedical Engineering, College of Engineering and Applied Sciences

C

Chunmei Lu

State Key Laboratory of Analytical Chemistry for Life Science, Department of General Surgery & Pathology, Nanjing Drum Tower Hospital, School of Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC)

Q

Qi Sun

Y

Yan Zhang

L

Luyan Wu

State Key Laboratory of Analytical Chemistry for Life Science, Department of General Surgery & Pathology, Nanjing Drum Tower Hospital, School of Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC)

M

Min Feng

T

Takanori Suzuki

Department of Chemistry, Faculty of Science, Hokkaido University, N10 W8, North-ward, Sapporo 060-0810, Japan

D

Deju Ye

State Key Laboratory of Analytical Chemistry for Life Science, Department of General Surgery & Pathology, Nanjing Drum Tower Hospital, School of Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC)