A C
                    <sub>1</sub>
                    -Homologative Trifluoromethylation: Light-Driven Decarboxylative Trifluoroethylation of Carboxylic Acids

Federico Belnome; Antonio Pulcinella; Stefano Bonciolini; Mattia Lepori; Oleksandr P. Datsenko; Zhen He; Matteo Gasparetto; Pavel K. Mykhailiuk; Bas de Bruin; Timothy Noël

doi:10.1021/jacs.5c21423

Journal of the American Chemical Society

A C <sub>1</sub> -Homologative Trifluoromethylation: Light-Driven Decarboxylative Trifluoroethylation of Carboxylic Acids

F Federico Belnome (Flow Chemistry Group, Van’t Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, Amsterdam 1098 XH, The Netherlands) A Antonio Pulcinella (Flow Chemistry Group, Van’t Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, Amsterdam 1098 XH, The Netherlands) S Stefano Bonciolini (Flow Chemistry Group, Van’t Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, Amsterdam 1098 XH, The Netherlands) M Mattia Lepori (Flow Chemistry Group, Van’t Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, Amsterdam 1098 XH, The Netherlands) O Oleksandr P. Datsenko (Enamine Ltd., Winston Churchill Str. 78, Kyiv 02094, Ukraine) Z Zhen He M Matteo Gasparetto (Flow Chemistry Group, Van’t Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, Amsterdam 1098 XH, The Netherlands) P Pavel K. Mykhailiuk (Enamine Ltd, Winston Churchill St. 78, 02094 Kyiv, Ukraine) B Bas de Bruin (Van ‘t Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands) T Timothy Noël (Flow Chemistry Group, Van’t Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, Amsterdam 1098 XH, The Netherlands)

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Article Details

Journal Journal of the American Chemical Society

Volume / Issue Vol. 148, Issue 7

Published February 25, 2026

Pages 7645-7654

DOI 10.1021/jacs.5c21423

ISSN 0002-7863

Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (10)

F

Federico Belnome

Flow Chemistry Group, Van’t Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, Amsterdam 1098 XH, The Netherlands

A

Antonio Pulcinella

Flow Chemistry Group, Van’t Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, Amsterdam 1098 XH, The Netherlands

S

Stefano Bonciolini

Flow Chemistry Group, Van’t Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, Amsterdam 1098 XH, The Netherlands

M

Mattia Lepori

Flow Chemistry Group, Van’t Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, Amsterdam 1098 XH, The Netherlands

O

Oleksandr P. Datsenko

Enamine Ltd., Winston Churchill Str. 78, Kyiv 02094, Ukraine

Z

Zhen He

M

Matteo Gasparetto

Flow Chemistry Group, Van’t Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, Amsterdam 1098 XH, The Netherlands

P

Pavel K. Mykhailiuk

Enamine Ltd, Winston Churchill St. 78, 02094 Kyiv, Ukraine

B

Bas de Bruin

Van ‘t Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands

T

Timothy Noël

Flow Chemistry Group, Van’t Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, Amsterdam 1098 XH, The Netherlands

A C <sub>1</sub> -Homologative Trifluoromethylation: Light-Driven Decarboxylative Trifluoroethylation of Carboxylic Acids

Article Details

Journal Info

Authors (10)

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