5′-Palmitate Lipid and Internal LNA-Piperidyl Triesters Enhance the RNA Affinity and Activity of Splice-Switching Oligonucleotides
D
Debashis Dhara
(Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K.)
T
Tom Brown
(Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K.)
Article Details
Volume / Issue
Vol. 148, Issue 24
Published
June 24, 2026
Pages
25198-25209
ISSN
0002-7863
Publisher
American Chemical Society
Journal Info
Journal of the American Chemical Society
American Chemical Society
ISSN: 0002-7863 Physical Sciences
Authors (2)
D
Debashis Dhara
Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K.
T
Tom Brown
Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K.
Related Articles from this Journal
Rational Design of the Composite Perfluoro-Sulfonic Ionomer for High-Performance Proton Exchange Membrane Fuel Cells
Tingting Mao, Haiyang Fan et al.
Jul 2026
10.1021/jacs.6c05625
Ti3+-O Acid–Base Pairs for Efficient Solar-Driven Photothermal Nonoxidative Ethane Dehydrogenation
Yuwen Sun, Kun Gong et al.
Jul 2026
10.1021/jacs.6c08665
Total Synthesis of Benthol A: Evidence for a Structure Revision
Guanghao Huang, Andrea Tomio et al.
Jul 2026
10.1021/jacs.6c05580
Accelerated Self-Photopolymerization of Phenolics in Microdroplets Contributes to the Brown Carbon Formation
Haoran Yu, Xinrui Yang et al.
Jul 2026
10.1021/jacs.6c10186
Deciphering the Specificity of Reversible DNA-Phosphate ADP-Ribosylation via the Precise Synthesis and Enzymatic Profiling of Nucleotide-Phospho-ADP-Ribosyl Probes
Lingxiao Liu, Yang Lu et al.
Jul 2026
10.1021/jacs.6c02874