Athukoralage, J. S., McMahon, S. A., Zhang, C., Grüschow, S., Graham, S., Krupovic, M., Whitaker, R. J., Gloster, T. M., White, M. F. (2025). Reply to: Natively expressed AcrIII-1 does not function as an anti-CRISPR protein. Nature. https://doi.org/10.1038/s41586-025-08650-7