Chang, T., Chen, W., Qu, C., Cheng, Z., Elsayed, A., Pounds, S. B., Shago, M., Rabin, K. R., Raetz, E. A., Devidas, M., Cheng, C., Angiolillo, A., Baviskar, P., Borowitz, M., Burke, M. J., Carroll, A., Carroll, W. L., Chen, I., Harvey, R., Heerema, N., Iacobucci, I., Wang, J. R., Jeha, S., Larsen, E., Mattano, L., Maloney, K., Pui, C., Ramirez, N. C., Salzer, W., Willman, C., Winick, N., Wood, B., Hunger, S. P., Wu, G., Mullighan, C. G., Loh, M. L. (2025). Reply to: Accurate Determinants of Outcome in ALL. Journal of Clinical Oncology. https://doi.org/10.1200/jco-24-02335