Savidge, A., Zhang, H., Adhav, V. A., Kehling, A. C., Sim, G., Shen, Z., Fu, T., Nakanishi, K. (2025). Neurodevelopmental disorder–linked Argonaute mutations permit delayed RISC formation and unusual shortening of miRNAs by 3′→5′ trimming. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.2524644122