Lee, E., Kim, W., Beier, D. H., Lee, Y., Kovalenko, M., Saif, F., Oliver, E., Srinageshwar, B., Murtha, R., Andrew, M. A., Jiang, A., Gillis, T., Demelo, B., Ruliera, J., Lucente, D., Kwak, S., Lee, R., Pinto, R. M., MacDonald, M. E., Gusella, J. F., O’Brien, P. J., Wheeler, V. C., Seong, I. S. (2026). Huntington’s disease LIG1 modifier variant increases ligase fidelity and suppresses somatic CAG repeat expansion. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.2518854123