Enzyme Enhancement Through Computational Stability Design Targeting NMR-Determined Catalytic Hotspots - Luis I. Gutierrez-Rus; Eva Vos; David Pantoja-Uceda; Gyula Hoffka; Jose Gutierrez-Cardenas; Mariano Ortega-Muñoz; Valeria A. Risso; Maria Angeles Jimenez; Shina C. L. Kamerlin; Jose M. Sanchez-Ruiz (Journal of the American Chemical Society, 2025)