Abstract 4462 IDO1 downregulation by its novel E3 ligase SHFM3 is modulated by Indoxyl Sulfate, exacerbating its prothrombotic effect - Ricardo Almiron; Abbas Malloum; David Wu Wong; Asha Jose; Saran Lotfollahzadeh; Kashvi Sethuraman; Katya Ravid; Vipul Chitalia (Journal of Biological Chemistry, 2026)